Leifer, Franziska,Omiatek, Donna M.,Ong, Jane,Gupta, Renu,Li, Zhilli,Perkins, Walter,Malinin, Vladimir
申请号:
AU2013351934
公开号:
AU2013351934A1
申请日:
2013.12.02
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to pharmaceutical compositions comprising a prostacyclin, a cationic compound, and a surfactant. Particulate compositions, including liposomal, solid nanoparticulate prostacyclin compositions, including treprostinil formulations comprising cationic compound and the surfactant are also described. The present invention also relates to a system comprising the pharmaceutical composition and an inhalation device. Methods for treating pulmonary hypertension and portopulmonary hypertension with the compositions and systems described herein are also provided.