Fraunhofer-Gesellschaft Zur Fõrderung Der Angeewandten Forschung E.V.
发明人:
Frank Emmrich,Stephan Fricke,Nadja Hilger
申请号：
US16078006
公开号：
US20190262396A1
申请日:
2017.02.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to an unmodified graft, a modified graft and/or a CD4 antagonist (preferably a CD4 antibody) for use in a method of treating one or more disease(s) treatable by transplantation in a subject, wherein said method comprises a first step of introducing into said subject a modified graft, and a second step of introducing into said subject said unmodified graft, wherein said modified graft is a cell graft containing immune cells, wherein said modification impairs CD4. The present invention also relates to various further uses of an unmodified graft, a modified graft and/or a CD4 antagonist.
