Christopher Dinsmore,Francesc Xavier Fradera Llinas,Amit Ashokro Kudale,Michelle Machacek,Michael Hale Reutershan,Christopher Francis Thompson,B. Wesley Trotter,Liping Yang,Michael D. Altman,Stephane
申请号：
US14652466
公开号：
US09637493B2
申请日:
2013.12.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides substituted pyrrolopyrimidines of Formula I as described herein or a pharmaceutically acceptable salt or solvate thereof:The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
