Method of Tissue-Selective Targeted Gene Transfer

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专利权人:

The Curators of the University of Missouri

发明人:

Rajiv R. Mohan

申请号：

US13683944

公开号：

US20130158103A1

申请日:

2012.11.21

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to methods of delivering a gene, such as a therapeutic gene, to a desired area of stroma of a cornea that involves removing the corneal epithelium and dehydrating the cornea. Certain aspects of the present invention relate to methods of treating corneal scarring by delivering a TGFβ-antagonizing gene packaged in a viral vector.

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