ABBOTT LABORATORIES;ABBVIE INC.;ABBOTT GMBH & CO. KG
发明人:
申请号：
IL20778710
公开号：
IL207787A
申请日:
2010.08.24
申请国别(地区):
IL
年份:
2016
代理人:
摘要：
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies have the ability to inhibit the binding of RGM A to its receptor and/or coreceptors. These antibodies or portions thereof of the invention are useful for detecting RGM A and for inhibiting RGM A activity, for example in a human suffering from a disorder including but not limited to multiple sclerosis, mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.
