The use of Titanium metal fine-particles for increasing of effect of the germicidal medicines used for human skin, skin infection and traumatism, is provided. The application of the Titanium metal fine-particles layer being laid on or close to skin, in combination with a medicine, functions to restrain bacteria breeding and multiplying, accelerate skin and dermic-organism metabolism, and promoting capillary purification. By these functions, an environment which is harmful and fatal for bacteria breeding/multiplying will be developed on the human body skin and dermic-organism. These functions are demonstrated by the increased effects of the germicidal medicines which are used for human skin dermatosis, skin infection and traumatism.