DÉRIVÉS DE 2-AMINO-QUINOLINE UTILISÉS COMME INHIBITEURS DE LA BETA -SÉCRÉTASE (BACE)

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

申请号：

EP09705822.6

公开号：

EP2240472B1

申请日:

2009.01.29

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention is directed to novel 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of &bgr；-secretase, also known as &bgr；-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/