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用於治療癌症的(S,E)-3-(6-氨基吡啶-3-基)-N-((5-(4-(3-氟-3-甲基吡咯烷-L-羰基)苯基)-7-(4-氟苯基)苯並呋喃-2-基)甲基)丙烯酰胺
专利权人:
KARYOPHARM THERAPEUTICS INC.;卡爾約藥物治療公司
发明人:
BALOGLU, Erkan,SHACHAM, Sharon,SENAPEDIS, William,S‧沙查姆,SENAPEDIS, William,W‧塞納佩迪斯
申请号:
HK18114602
公开号:
HK1255438A1
申请日:
2018.11.15
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
The invention generally relates to substituted benzofuranyl compounds and, more particularly, to a compound represented by Structural Formula la: (I) or a pharmaceutically acceptable salt thereof. The invention also includes the synthesis and use of the compound of Structural Formula la, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of diseases or disorder selected from cancer (e.g., lymphoma, such as mantle cell lymphoma), a neurodegenerative disease, an inflammatory diseases or an immune system disease (e.g., a T-Cell mediated autoimmune disesase) in a subject in need thereof. The method comprises administering to a subject in need thereof a therapeutically effective amount of a compound of the invention, or a pharmaceutically acceptable salt thereof, or a composition comprising a compound of the invention, or a pharmaceutically acceptable salt thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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