Ｎ－羥基－４－｛２－［３－（Ｎ，Ｎ－二甲基胺基甲基）苯並呋喃－２－基羰基胺基］乙氧基｝苯甲醯胺之新穎投藥法农业专利-农业专业知识服务系统

发明人:: KLOOS, IOANA,克鲁斯　伊欧纳,克魯斯　伊歐納,ROBERT, RENATA,罗伯特　瑞诺塔,羅伯特　瑞諾塔,JACQUET-BESCOND, ANNE,杰科特　贝司康得　安,傑科特　貝司康得　安,DEPIL, STEPHANE,德皮尔　史戴芬,德皮爾　史戴芬,CHENEL, MARYLORE,雪耐儿　玛丽罗尔,雪耐兒　瑪麗羅爾,FOULIARD, SYLVAIN,福利雅德　席芽凡,福利,克鲁斯伊欧纳,克魯斯伊歐納,罗伯特瑞诺塔,羅伯特瑞諾塔,杰科特贝司康得安,傑科特貝司康得安,德皮尔史戴芬,德皮爾史戴芬,雪耐儿玛丽罗尔,雪耐兒瑪麗羅爾,福利雅德席芽凡

摘要：: N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy}-benzamide of formula (I): or an addition salt thereof with a pharmaceutically acceptable acid or base, alone or in association with a surgery, chemotherapy, hormone therapy treatment or radiotherapy, for use in the treatment of cancer, characterised in that it is administered for 4 consecutive days, that period being followed by 3 consecutive days without any administration of compound of formula (I), with the proviso that chemotherapy is not FOLFOX. Medicaments.本發明係關於式(I)之N-羥基-4-{2-[3-(N,N-二甲基胺基甲基)苯並呋喃-2-基羰基胺基]乙氧基}苯甲醯胺或其與醫藥上可接受之酸或鹼之加成鹽：其係單獨使用或與手術、化學療法、激素療法治療或放射療法聯合使用，以治療癌症，特徵在於其係經投與連續4天，其後接著連續3天未投與任何式(I)化合物，但其限制條件係該化學療法不為FOLFOX。本發明提供藥物。