The invention relates to a composition for external application for care of skin, oral cavity, scalp or hair, especially for treating acne. The present inventors have found that a molecule andrographolide, present in extract of Andrographis paniculata, heretofore known to provide skin lightening and barrier protection to skin is a very potent anti-inflammatory agent. Further, they have found that a composition comprising this molecule along with antimicrobial agents can be used to treat acne.
