A coupling device (1) for connecting two ends (3, 9) of respective tubular members,allow the opening and the closing of a first tubular member and the simultaneousengagement of the two tubular members, in such a way preventing any pollution,comprises: a first case (5) housing a first end (3) of a respective first tubularmember (2), comprising closing means (10) of said first end (3)； a second case(20), wherein a flexible terminal section (6) of a respective second tubularmember is received, comprising means for driving a second end (9) of said secondtubular member from a retracted position to a engagement position into said firstend (3) and vice versa； and means for reversibly connecting said first and secondcases (5, 20) at a respective coupling port thereof, defining a single sealedenvironment； wherein the engagement and the disengagement of said second end(9) and the automatic mechanical activation and deactivation of said closingmeans (10) for opening and closing said first end (3).
