Luis Brito,Michelle Chan,Andrew Geall,Derek O'Hagan,Manmohan Singh,Derek OHagan
申请号:
US14130886
公开号:
US09636410B2
申请日:
2012.07.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines.