JAESCHKE, GEORG,LINDEMANN, LOTHAR,MARTIN, RAINER E.,RICCI, ANTONIO,RUEHER, DANIEL,STADLER, HEINZ,VIEIRA, ERIC
申请号:
SG11201510607R
公开号:
SG11201510607RA
申请日:
2014.07.04
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
The present invention relates to ethynyl derivatives as metabotropic glutamate receptor antagonists (negative allosteric modulators) for use in the treatment of, e.g., anxiety and pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD).