Alicia Regueiro-Ren,Zheng Liu,Jacob Swidorski,Nicholas A. Meanwell,Sing-Yuen Sit,Jie Chen,Yan Chen,Ny Sin
申请号:
US13151722
公开号:
US08802661B2
申请日:
2011.06.02
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 and C-28 betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.