A manual transfer vest which aids in compensating for fatigue, pain, loss of strength, mobility, and energy in the daily life of a patient or individual/caregiver assisting the patient. It comprises soft, lightweight, and preferably washable material that enwraps the patients torso, and also has at least two vertically-extending and non-adjustable hand-grip lift components with sturdy and durable construction and attachment. In most embodiments, six hand-grip lift components are used, with two upper front hand-grips preferably situated bilaterally in the clavicle/upper chest area of the patient, or the shoulder area, two lower front hand-grips situated bilaterally in the abdominal/mid-section area of the patient, and two upper back hand-grips located near the shoulders. For vest durability during repeated patient lifting, reinforcement lining material is also secured to the front exterior of the vest diagonally below hand-grips. Overall, the manual transfer vest promotes safety in preventing injuries, thereby reducing medical costs.