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ENHANCED MOISTURE BARRIER IMMEDIATE RELEASE FILM COATING SYSTEMS, SUBSTRATES COATED THEREWITH AND METHODS PRODUCING THE SAME
专利权人:
BPSI HOLDINGS; INC.
发明人:
申请号:
IL21624111
公开号:
IL216241D0
申请日:
2011.11.09
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.
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