To offer medicine, food and drink which rise concentration of Adiponectin in blood and are safe enough to intake for a long period. An agent for rising concentration of Adiponectin comprising educt of guava leaves.本發明係提供一種醫藥品及飲食品,其具有提昇血中脂聯素(Adiponectin)濃度之作用,且可長期攝取、安全性較高。本發明係關於一種脂聯素濃度上升劑,其係以番石榴葉萃取物作為有效成分。