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Modulation of apolipoprotein ciii (apociii) expression
专利权人:
ISIS PHARMACEUTICALS INC.
发明人:
MULLICK ADAM,CROOKE ROSANNE M.,GRAHAM MARK J.,DOBIE KENNETH W.,BELL THOMAS A.,LEE RICHARD
申请号:
NZ61677912
公开号:
NZ616779A
申请日:
2012.04.27
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a use of a compound targeting ApoCIII in the manufacture of a medicament for a) treating, preventing, delaying or ameliorating pancreatitis in an animal; b) increasing HDL levels and/or improving the ratio of TG to HDL in an animal thereby preventing, delaying or ameliorating a cardiovascular disease, disorder, condition or symptom thereof or onset of a cardiovascular disease, disorder, condition or symptom thereof in an animal; c) increasing HDL levels and/or improving the ratio of TG to HDL in an animal thereby reducing the risk of a cardiovascular disease, disorder, condition or symptom in an animal; and/or d) treating, preventing, delaying or ameliorating chylomicronemia, wherein the compound is capable of inhibiting apolipoprotein C-III.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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