An expandable support structure and methods of use for treatment of a patients cerebral aneurysm are described. The support structure includes a plurality of elongate support members each having first and second ends that are both gathered at the first end of the support structure. Each elongate support member starts at the first end of the support structure, extends to an apex at the second end of the support structure, and extends back to the first end of the support structure. The support structure has a low profile, radially constrained state having a low profile suitable for delivery from a microcatheter. The support structure also has an expanded relaxed state that defines a substantially globular shape. In the expanded relaxed state, the apices of the elongate support members are arranged to define an open distal end.