United States Government as represented by the Department of Veterans Affairs;The Regents of the University of California
发明人:
申请号：
EP17793216.7
公开号：
EP3452447A4
申请日:
2017.05.03
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
This disclosure relates to inhibitors of IRES-mediated protein synthesis, compositions comprising therapeutically effective amounts of these compounds, and methods of using those compounds and compositions in treating hyperproliferative disorders, e.g., cancers. This disclosure also relates to compositions comprising inhibitors of IRES-mediated protein synthesis and mTOR inhibitors, and to methods of treating cancer by conjoint administration of inhibitors of IRES-mediated protein synthesis and mTOR inhibitors.
