PARK, SUN MIN,박선민,KIM, HYUN RYOUNG,김현령,PARK, JAE CHAN,박재찬,CHAE, SU YOUNG,채수영
申请号：
KR1020130011992
公开号：
KR1020130089213A
申请日:
2013.02.01
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A solid lipid nanoparticle is provided to offer an effective method for transferring an active ingredient to the target site of body.CONSTITUTION: A solid lipid nanoparticle comprises an elastin-like polypeptide in which the moiety having more than one hydrophobic groups are bound and lipid molecule. The moiety having hydrophobic group is the saturated or unsaturated hydrocarbon group, the saturated or unsaturated acyl group, the substitute amide group having a chemical formula -C(CO)N(R1)(R2), which means the R1 and R2 are the respectively independent saturated or unsaturated hydrocarbon, or the saturated or unsaturated alkoxy group. The lipid molecule is neutral lipid molecule or amphiphilic lipid molecule. The elastic-like polypeptide includes more than one repeat unit selected from among VPGXG, PGXGV, GXGVP, XGVPG, GVPGX, and a group comprised of combination thoseof more than once. The V, P, G, and X is respectively means valine, proline, glycine, and an amino acid which is not proline.COPYRIGHT KIPO 2013[Reference numerals] (AA) Coefficient엘라스틴-유사 폴리펩티드를 포함하는 고형 지질 나노입자 및 그의 용도를 제공한다.
