BOURNE, GREGORY,BHANDARI, ASHOK,CHENG, XIAOLI,FREDERICK, BRIAN TROY,ZHANG, JIE,PATEL, DINESH V.,LIU, DAVID
申请号：
CA2955460
公开号：
CA2955460A1
申请日:
2015.07.15
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease. In a first aspect, the present invention provides a peptide inhibitor of an interleukin-23 receptor, or a pharmaceutically acceptable salt or solvate thereof, wherein the peptide inhibitor comprises an amino acid sequence of Formula (Xa). In another aspect, the present invention includes a pharmaceutical composition comprising a peptide inhibitor or a peptide dimer inhibitor of the present invention, and a pharmaceutically acceptable carrier.
