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NOVEL MUCOSAL VACCINATION APPROACH FOR HERPES SIMPLEX VIRUS TYPE-2
专利权人:
Dennis I. Guberski;Kejian Yang
发明人:
Kejian Yang,Dennis I. Guberski
申请号:
US13583845
公开号:
US20130195961A1
申请日:
2011.03.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2 are provided. The protective immune response elicited by the methods and kits is characterized by robust humoral, cellular, and mucosal immunity. In particular, a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes is provided. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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