ALEXANDER FLOHR,ROLAND JAKOB-ROETNE,WOLFGANG WOSTL
申请号:
BRPI0807341
公开号:
BRPI0807341A2
申请日:
2008.01.23
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The invention relates to 6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl derivatives of formula I wherein R1, R2 and R3 are as defined herein. The compounds are gamma-secretase inhibitors useful in the treatment of Alzheimer's disease or common cancer, including, but not limited to, cervical carcinomas and breast carcinomas and malignancies of the hematopoietic system.