The present invention is to provide a medical composition for the treatment or prophylaxis of diseases caused by angiogenesis of eyes which comprises a compound represented by the following formula (I):wherein R1 represents a C1-C6 alkyl group or halogeno-C1-C6alkyl group, R2 represents a carboxyl group which may be protected, and Y represents a group represented by the formula (II):wherein Z represents CH or nitrogen atom,or a pharmaceutically acceptable salt thereof as an active ingredient.
