PETRUKHIN KONSTANTIN,ALLIKMETS RANDO,JOHNSON GRAHAM,CIOFFI CHRISTOPHER,FREEMAN EMILY,CHEN PING,CONLON MICHAEL,ZHU LEI
申请号：
IN201617038843
公开号：
IN201617038843A
申请日:
2016.11.15
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention provides a compound having the structure: wherein Ri, R2, R3, R4, and are each independ ently H, halogen, CF or C 1 alkyl, wherein two or more of Ri, R2, R3, R4, or R5 are other than H R is H, OH, or halogen and B is a substituted or unsubstituted heterobicycle, wherein when R i is CF , R2 is H, R is F , R is H, and is H, or R i is H, R2 is CF , R3 is H, R is CF , and R5 is H, or R i is Ci, R2 is H, R is H, R is F , and R5 is H, or R i is CF , R2 is H, R is F , R is H, and R5 is H, or R i is CF , R2 is F , R is H, R is H, and is H, or R i is Ci, R2 is F , R is H, R is H, and is H, then B is other than or a pharma ceutically acceptable salt thereof.
