DETERMINING SENSITIVITY OF CELLS TO B-RAF INHIBITOR TREATMENT BY DETECTING KRAS MUTATION AND RTK EXPRESSION LEVELS

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专利权人:

发明人:

Georgia Hatzivassiliou,Shiva Malek

申请号：

US14284027

公开号：

US20150164895A1

申请日:

2014.05.21

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to prognostic methods for identifying tumors that are not susceptible to B-Raf inhibitor treatment by detecting mutations in a K-ras gene or protein or by detecting overexpression of RTKs and/or their ligands. Kits are also disclosed for carrying out the methods.

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中国工程科技知识中心

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http://www.ckcest.cn/home/