Dissaya Pornpattananangkul;Chun-Ming E. Huang;Liangfang Zhang
发明人:
Liangfang Zhang,Dissaya Pornpattananangkul,Chun-Ming E. Huang
申请号：
US13607094
公开号：
US20130028962A1
申请日:
2012.09.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Control of the fusion activity of liposomes by adsorbing biocompatible nanoparticles to the outer surface of phospholipid liposomes is disclosed. The biocompatible nanoparticles effectively prevent liposomes from fusing with one another. Release of cargo from the liposome is accomplished via trigger mechanisms that include pH triggers, pore forming toxing triggers and photosensitive triggers. Dermal drug delivery to treat a variety of skin diseases such as acne vulgaris and staph infections is contemplated.
