Zhang, Liangfang,Pornpattananangkul, Dissaya,Huang, Chun-Ming, E.
申请号：
AU2011224257
公开号：
AU2011224257A1
申请日:
2011.03.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
A new approach to control the fusion activity of liposomes by adsorbing biocompatible nanoparticles to the outer surface of phospholipid liposomes is disclosed. The biocompatible nanoparticles effectively prevent liposomes from fusing with one another. Release of cargo from the liposome is accomplished via trigger mechamisms that include pH triggers, pore forming toxing triggers and photosentisitve triggers. Dermal drug delivery to treat a variety of skin diseases such as acne vulgaris and staph infections is comtemplated.
