This invention designates the improvement of basal metabolism as operation mechanism unlike the curative medicine of the degenerative disease by existing biochemical reaction inhibition die, there is no side effect, it offers the medicine constituent and the preventive remedy manner medicine tolerance of the degenerative disease does not occur of the degenerative disease which uses that. The 5 amino levulin Acid (ALA) or that derivative or those salts is contained, desirably it contains with iron compound such as ALA or that derivative or those salts and citric acid ferrous sodium, citric acid iron sodium and ferricammonium citrate, metabolic syndrome, diabetes and the hyperlipemia symptom, the hypertension, liver dysfunction, kidney incompletion and obesity, happening incompletion and the change of life fault, the food or the food material and this constituent for prevention improvement of degenerative disease which adds the preventive improvement constituent and the said constituent of the degenerative disease of stiff shoulders and the lumbago etc the preventive improvement medicine of the degenerative diseaseThe manner and the like which is used for preparation is offered.本発明は、既存の生化学反応阻害型による成人病の治療薬と異なり、基礎代謝の向上を作用メカニズムとする、副作用が無く、成人病の薬剤耐性が生じない薬剤組成物や、それを用いた成人病の予防・治療方法を提供する。5-アミノレブリン酸(ALA)若しくはその誘導体又はそれらの塩を含有する、好ましくはALA若しくはその誘導体又はそれらの塩と、クエン酸第一鉄ナトリウム、クエン酸鉄ナトリウム、クエン酸鉄アンモニウム等の鉄化合物とを含有する、メタボリックシンドローム、糖尿病、高脂血症、高血圧、肝機能障害、腎不全、肥満、勃起不全、更年期障害、肩こり、腰痛等の成人病の予防・改善組成物や、該組成物を添加した成人病の予防・改善用食品又は食品素材や、かかる組成物を成人病の予防・改善剤の調製に使用する方法等を提供する。
