PROBLEM TO BE SOLVED: To obtain an antistress agent and a central fatigue ameliorant.SOLUTION: The preventive antistress agent comprises a chlorogenic acid or its pharmaceutically permissible salt as an active ingredient. The central fatigue ameliorant comprises a chlorogenic acid or its pharmaceutically permissible salt as an active ingredient.COPYRIGHT: (C)2007,JPO&INPIT【課題】抗ストレス剤及び中枢性疲労改善剤の提供。【解決手段】クロロゲン酸類又はその薬学的に許容される塩を有効成分とする予防的抗ストレス剤及び中枢性疲労改善剤。【選択図】なし