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EP4 agonist
专利权人:
Kaken Pharmaceutical Co., Ltd.;Asahi Glass Company, Limited
发明人:
Takahiko Murata,Masahiro Amakawa,Shin Teradaira,Yasushi Matsumura,Katsuhiko Konishi
申请号:
US13675530
公开号:
US08691857B2
申请日:
2012.11.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided is a compound represented by the formula (1):wherein R1 and R2 are each independently a hydrogen atom or a straight chain alkyl group having a carbon number of 1-3, R3 is a hydrogen atom, an alkyl group having a carbon number of 1-4, an alkoxyalkyl group, an aryl group, a halogen atom or a haloalkyl group, or a pharmaceutically acceptable salt thereof, which has, unlike known PGI2 analogs, a selective EP4 agonist action, and a medicament containing the compound, which is useful for the prophylaxis and/or treatment of immune diseases, diseases of the digestive tract, cardiovascular diseases, cardiac diseases, respiratory diseases, neurological diseases, ophthalmic diseases, renal diseases, hepatic diseases, bone diseases, skin diseases and the like.
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中国工程科技知识中心
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