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Platinum compounds to treat cell proliferation diseases, preparation procedures and uses thereof
专利权人:
BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT; CO.; LTD
发明人:
CHEN, Xiaoping,YAN, Yashi,MENG, Xiaoping,ZHAO, Feng,GAO, Zejun,WEN, Shouming
申请号:
ES12811424
公开号:
ES2668470T3
申请日:
2012.07.06
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A compound of formula A, or a pharmaceutically acceptable salt, solvate, racemate, non-enantiomer or geometric isomer thereof ** (See formula) ** in which: R1 and R2, are the same or different, are selected between hydrogen; I rent; optionally substituted saturated hydrocarbon rings containing 1 to 3 rings and each ring contains 3 to 7 carbon atoms; alkoxyalkyl; alkylaminoalkyl; heterocycle; a straight chain or branched chain alkyl group having 1 to 4 ethylenic bonds containing 2 to 20 carbon atoms; and a straight chain or branched chain alkyl group with 1 to 4 acetylenic bonds containing 2 to 20 carbon atoms; where hydrocarbyl; alkoxyalkyl; alkylaminoalkyl and heterocycle are unsubstituted or optionally substituted, preferably substituted with halogen, hydroxy, alkoxy, alkyl, alkoxyalkyl, optionally substituted saturated hydrocarbon ring containing from 1 to 3 rings and each ring contains from 3 to 7 carbon atoms, and heterocycle ; provided that R1 or R2 do not contain any unsaturated bonds, or if R1 and / or R2 contain an unsaturated bond, the unsaturated bond atom cannot be connected directly to the nitrogen atom; R3 is selected from alkyl, an optionally substituted saturated hydrocarbon ring containing 1 to 3 rings and each ring contains 3 to 7 carbon atoms; R4 and R5, are the same or different, selected from: hydrogen; hydroxyl; I rent; optionally substituted saturated hydrocarbon rings containing 1 to 3 rings and each ring contains 3 to 7 carbon atoms; alkoxy; alkoxyalkyl; heterocycle; a straight chain or branched chain alkyl group having 1 to 4 ethylenic bonds containing 2 to 20 carbon atoms; a straight chain or branched chain alkyl group with 1 to 4 acetylenic bonds containing 2 to 20 carbon atoms; wherein alkyl, a straight chain or branched chain alkyl group with 1 to 4 ethylenic bonds containing 2 to 20 carbon atoms, a straight chain or branched chain alkyl group having 1 to 4 acetylenic bonds containing 2 to 20 carbon atoms, an optionally substituted satu
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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