Pim kinase inhibitors and methods of their use

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专利权人:

NOVARTIS AG

发明人:

BURGER, MATTHEW,LINDVALL, MIKA,HAN, WOOSEOK,LAN, JIONG,NISHIGUCHI, GISELE,SHAFER, CYNTHIA,BELLAMACINA, CORNELIA,HUH, KAY,ATALLAH, GORDANA,MCBRIDE, CHRISTOPHER,ANTONIOS-MCCREA JR., WILLIAM,ZAVOROTINSKA

申请号：

AU2012202993

公开号：

AU2012202993A1

申请日:

2012.05.22

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

[--NR~nblDCCKNG431752_I D)OC-2 /5 2l New compounds, compositions and methods of inhibition of kinase activity associated with tLumorigcnesis in a human or animal subject are provided. In certain embodiments. the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The nCw compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/