The present invention relates to a pharmaceutical composition for promoting differentiation of cardiomyocytes derived from embryonic stem cells containing Echinochrome A as an active ingredient. More specifically, since it has been confirmed that Echinochrome A extracted from Plococidaris verticillata of Echinodermata exhibits non-cytotoxicity and effectively induces differentiation from mouse embryonic stem cells into cardiomyocytes, the composition containing Echinochrome A as an active ingredient according to the present invention may be provided as a composition or a medium composition for inducing differentiation of cardiomyocytes.La présente invention concerne une composition pharmaceutique permettant de favoriser la différenciation de cardiomyocytes dérivés de cellules souches embryonnaires comprenant de léchinochrome A en tant que principe actif. Plus précisément, étant donné quil a été confirmé que léchinochrome A extrait de Plococidaris verticillata des échinodermes présente une non-cytotoxicité et induit efficacement la différenciation de cellules souches embryonnaires de souris en cardiomyocytes, la composition comprenant de léchinochrome A en tant que principe actif, selon la présente invention, peut être fournie en tant que composition ou composition de milieu permettant dinduire la différenciation de cardiomyocytes.본 발명은 에키노크롬 A(Echinochrome A)를 유효성분으로 함유하는 배아줄기세포 유래 심근세포 분화촉진용 약학조성물에 관한 것으로, 보다 상세하게는 극피동물 성게류에서 추출된 에키노크롬 A는 세포독성을 나타내지 않으며 생쥐 배아줄기세포에서 심근세포로의 분화를 효과적으로 유도하는 것으로 확인됨에 따라 본 발명에 따른 에키노크롬 A를 유효성분으로 함유하는 조성물은 심근세포 분화유도용 조성물 또는 배지조성물로 제공될 수 있다.
