CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION;가톨릭관동대학교산학협력단
发明人:
HWANG, Ki-Chul,황기철,LIM, Soyeon,임소연,KIM, Sang Woo,김상우,LEE, Yunmi,이윤미,CHOI, Jung Won,최정원
申请号：
KRKR2018/012555
公开号：
WO2019/088546A2
申请日:
2018.10.23
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention relates to a use of a kenpaullone derivative for inducing the differentiation of a stem cell into a cardiomyocyte, and, more specifically, a kenpaullone derivative according to the present invention has excellent capability for inducing the differentiation of a stem cell into a cardiomyocyte, and the cardiomyocyte obtained by the kenpaullone derivative-induced differentiation has an excellent therapeutic effect for cardiopathy such as myocardial infarction.La présente invention concerne l'utilisation d'un dérivé de kenpaullone pour induire la différenciation d'une cellule souche en cardiomyocyte.Plus spécifiquement, le dérivé de kenpaullone selon la présente invention a une excellente capacité pour induire la différenciation d'une cellule souche en cardiomyocyte, et le cardiomyocyte obtenu par la différenciation induite par ledit dérivé de kenpaullone a un excellent effet thérapeutique sur les cardiopathies telles que l'infarctus du myocarde.본 발명은 켄파울론 유도체의 줄기세포의 심근세포로의 분화 유도 용도에 관한 것으로, 보다 상세하게는, 본 발명의 켄파울론 유도체는 줄기세포로부터 심근세포로의 분화 유도능이 우수하고, 켄파울론 유도체에 의해 분화 유도된 심근세포는 심근경색 등 심장질환의 치료적 효과가 우수하다.
