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PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF
专利权人:
LOXO ONCOLOGY, INC.;ARRAY BIOPHARMA INC
发明人:
SPENCER, Stacey,ZHAO, Qian,EARY, Charles Todd,HAAS, Julia,JIANG, Yutong
申请号:
CR20190255
公开号:
CR20190255A
申请日:
2017.10.26
申请国别(地区):
CR
年份:
2019
代理人:
摘要:
In some embodiments, processes for preparing a compound of Formula C, or a salt thereof, are provided herein as described herein. In some embodiments, there is provided herein a compound of Formula I, or a pharmaceutically acceptable salt, solvate, or hydrate thereof. In some embodiments, a solid form of the compound, such as a crystalline form of the crystalline Form I of the compound, is provided herein.In some embodiments, provided herein are processes for preparing a compound of Formula C or a salt thereof, as disclosed herein. In some performances,provided herein is a compound of Formula I or a pharmaceutically acceptable salt solvate or hydrate thereof In some embodiments provided herein is a solid form of the compound such as a crystalline form of the compound crystalline Form IEn algunas formas de realización, se proporcionan en la presente procesos para preparar un compuesto de la Fórmula C, o una sal de este, como se describe en la presente. En algunas formas de realización, se proporciona en la presente un compuesto de la Fórmula I, o una sal, solvato o hidrato de este aceptable desde el punto de vista farmacéutico. En algunas formas de realización, se proporciona en la presente una forma sólida del compuesto, tal como una forma cristalina de la Forma I cristalina del compuesto.In some embodiments, provided herein are processes for preparing a compound of Formula C or a salt thereof, as disclosed herein. In some embodiments, provided herein is a compound of Formula I or a pharmaceutically acceptable salt, solvate or hydrate thereof. In some embodiments, provided herein is a solid form of the compound, such as a crystalline form of the compound crystalline Form I.
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