Fibroblast growth factor (FGF) remodeling and carbohydrate pegylation

• 收藏
• 分享

专利权人:

レイショファーム ゲーエムベーハー

发明人:

デフリース，シャウン,デフリース,シャウン

申请号：

JP2007539238

公开号：

JP5948627B2

申请日:

2005.10.31

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention relates to mutants of Fibroblast Growth Factor (FGF), particularly FGF-20 and FGF-2 1, which contain newly introduced N-linked or O-linked glycosylation site(s). The polynucleotide coding sequences for the mutants, expression cassettes comprising the coding sequences, cells expressing the mutants, and methods for producing the mutants are also disclosed. Further disclosed are pharmaceutical compositions comprising the mutants and method for using the mutants.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/