The present invention relates to bispecific constructs that specifically bind to immune effector cells and at the same time bind to target cells carrying IL23R, as well as nucleic acids, vectors, host cells, pharmaceutical compositions, and their production, and It relates to methods of their use, including the use of such bispecific constructs in the treatment of inflammatory and / or autoimmune diseases and / or cancer. [Selection] Figure 1本発明は、免疫エフェクター細胞に特異的に結合し、同時にIL23Rを担持する標的細胞に結合する、二重特異性構築物、並びに核酸、ベクター、宿主細胞、医薬組成物、並びに、それらの製造、並びに炎症性及び/又は自己免疫性疾患及び/又は癌の治療におけるそのような二重特異性構築物の使用を含む、それらの使用方法に関する。【選択図】図1