This invention offers the method of remedying the transfer characteristic cancer of the colon or the rectum new crystal form and those production methods of irinotekan hydrochloride, making use of the medicine composition which includes the said new crystal form, and that.本発明は、イリノテカン塩酸塩の新規な結晶形およびそれらの製造方法、該新規な結晶形を含む医薬組成物、ならびにそれを用いて結腸もしくは直腸の転移性癌を治療する方法を提供する。