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Polyurethane having an antithrombogenic coating
专利权人:
pfm medical titanium gmbh
发明人:
Karin Stadtherr,Christof Schmid,Karla Lehle,Karin Lukas,Hanngörg Zimmermann,Daniel Wehner,Thomas Schmid
申请号:
US15036806
公开号:
US09867912B2
申请日:
2014.11.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention concerns polyurethane (PUR) having an antithrombogenic coating, wherein the antithrombogenic coating comprises at least one antithrombogenic substance covalently bound to a surface of the PUR via at least two bonds, wherein a first of said bonds is an amide bond between the surface of the PUR and a polyethyleneimine (PEI) and a second of said bonds is between the PEI and the antithrombogenic substance, wherein the surface of the PUR had been activated by use of a carbon dioxide plasma or a plasma modified by addition of carbon dioxide before the first of said bonds was formed.
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