The present invention provides a method of biosynthesizing a recombinant protein containing the biologically active peptide, the pharmaceutical composition containing the recombinant protein as well as the preparation of the recombinant protein. Simply speaking the consecutively multiple copies of the bioactive peptide are replaced in the amino acid sequence of a recombinant protein (so called peptide protein). Then, a high concentration and high yield of the peptide protein containing the consecutively multiple copies of the bioactive peptide is bioproduced by the biosafety and edible strain of yeast without any endotoxin contamination.發明提供一種含有生物活性胜肽的重組蛋白質、含有該重組蛋白質的醫藥組成物以及該重組蛋白質之製備方法，其將連續多套的生物活性胜肽置換於一個蛋白質中，再由無毒性安全可食用之酵母菌大量生產富含連續多套生物活性胜肽的高濃度胜肽蛋白。
