This invention, regards, the prevention and remedy of brain dysfunction such as reinforcement of receptor function with the synapse inside the brain network which bears higher-order behavior. These brain networks, the acknowledgment talent which it is related to dysmnesia, for example the various acknowledgment symptoms, and nervous activity between the brain territory which differs being lop-sided, the thing and the parkinsons disease which are observed, participate in those and the like which are suggested with obstacle such as integrated malfunction symptom, and feelings obstacle. In the feature of specification, this invention regards the method of using this chemical compound for disposal of that kind of state because of useful chemical compound, and that kind of disposal.本発明は、高次挙動を担う脳ネットワーク内のシナプスでの受容体機能の増強など、脳機能不全の予防および治療に関する。これらの脳ネットワークは、記憶障害に関連する認知能、例えば様々な認知症、および異なる脳領域間の神経活動の不均衡で観察されるもの、パーキンソン病、統合失調症、および情動障害などの障害で示唆されるものなどに関与する。特定の態様において、本発明は、そのような状態の処置に有用な化合物、およびそのような処置のためにこの化合物を使用する方法に関する。