The present disclosure relates to the injection composition containing acetaminophen, the injection composition comprising acetaminophen mixed in 0.01∼5 wt%, a solubilizer mixed in 0.01∼10 wt%, a toxicity inhibitor mixed in 0.05∼5 wt%, an isotonic agent mixed in 0.1∼10 wt%, an antioxidant mixed in 0.001∼5 wt%, and the balance sterile purified water for injection.