PRABAKARAN, THANEAS,PALUDAN, RIIS SOREN,JAKOBSEN, MARTIN ROELSGAARD,PALUDAN, RIIS, SOREN,JAKOBSEN ROELSGAARD, MARTIN
申请号:
CA3090659
公开号:
CA3090659A1
申请日:
2019.02.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to tools for modulating the P62-STING interaction as a method for modulating the innate immune response. The invention relates to compounds which are capable of either inhibiting or potentiating the interaction and thereby induce or prevent the innate immune response relating to STING. Specifically, compounds are provided for use in the treatment of disorders associated with STING activity, including cancer and immuno-deficient or auto-immune disorders.