According to features of the present invention, provided is an HIFU operation apparatus comparing: a cartridge (110) including a case (111) having a long hole type output hole (112) provided on one side, and an ultrasound module (113) mounted in the case (111) to be able to reciprocate through sliding and having a transducer (114) mounted on an end portion to oscillate a high-intensity focused ultrasound (HIFU) through the output hole (112) a hand piece (120) having one side at which the cartridge (110) is detachably installed, and an actuator (121) installed inside to provide driving force necessary for sliding while pushing or pulling the ultrasound module (113) a controller (130) for driving and controlling the actuator (121) to allow the ultrasound module (113) to slide at a predetermined interval along the output hole (112) from a predetermined start alignment position (P), and driving and controlling the transducer (114) to perform ultrasonic oscillation in synchronization with the timing shifted to a predetermined interval and an arrangement sensor (140) for sensing whether the ultrasound module (113) is located at the start alignment position (P), wherein the controller includes a safety function for blocking the ultrasonic oscillation and alarming the non-alignment state through a display unit (150) if it is determined that the ultrasound module (113) is not located at the start alignment position (P) in response to the sensing signal of the alignment sensor (140) when the driving of the ultrasonic oscillation begins.COPYRIGHT KIPO 2016본 발명의 특징에 따르면, 일측에 장공의 출력공(112)이 마련된 케이스(111) 및, 상기 케이스(111) 내에서 슬라이딩 왕복이동이 가능하게 장착되며 단부에는 상기 출력공(112)을 통해 고강도집속 초음파(HIFU)를 발진하는 트랜스듀서(114)가 장착된 초음파모듈(113)을 포함하는 카트리지(110) 일측에는 상기 카트리지(110)가 착탈가능하게 장착되며 내부에는 상기 초음파모듈(113)을 밀거나 잡아당기면서 슬라이딩 이동하는데 필요한 구동력을 제공하는 액추에이터(121)가 장착된 핸드피스(120) 상기 초음파모듈(113)이 기설정된 시작정렬위치(P)에서 출력공(112)을 따라 일정간격으로 슬라이딩 이동하도록 액추에이터(121)를 구동제어하며, 상기 일정간격으로 이동한 타이밍에 동기하여 초음파를 발진하도록 트랜스듀서(114)를 구동제어하는 제어부(130