The Board of Trustees of the Leland Stanford Junior University
发明人:
Mark A. Kay,Matt Tiffany
申请号:
US15366863
公开号:
US10406244B2
申请日:
2016.12.01
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to AAV vectors encoding variant capsid polypeptides that are more cationic as compared to a non-variant parent capsid polypeptide and/or another variant capsid polypeptide, and wherein the vector comprising the variant capsid polypeptide is capable of comprising a longer nucleic acid insert as compared to a vector encoding a non-variant parent capsid polypeptide and/or another variant capsid polypeptide.