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Method of synthesizing thyroid hormone analogs and polymorphs thereof
专利权人:
F. HOFFMANN-LA ROCHE LTD.;MADRIGAL PHARMACEUTICALS INC.
发明人:
Taub, Rebecca,Hester, D.,Duguid, Robert,Kelly, Martha,Chasnoff, Anna,Dong, Gang,Crow, Edwin,Reynolds, Charles,Choi, Duk,Shu, Lianhe,Wang, Ping
申请号:
NZ70582713
公开号:
NZ705827A
申请日:
2013.09.17
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
The disclosure describes methods of synthesis of compounds of Formula (IV). Preferred methods according to the disclosure allow for large-scale preparation of compounds of Formula (IV) having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of compounds of Formula (IV) in better yield than previously used methods for preparing such compounds.
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