Porcine reproductive and respiratory syndrome virus resistant animals

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专利权人:

The Curators of the University of Missouri

发明人:

Prather, Randall S.

申请号：

AU2012255744

公开号：

AU2012255744A1

申请日:

2012.05.16

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The disclosure relates to genetically modified swine wherein at least one allele of a SIGLEC1 gene has been inactivated and/or at least one allele of a CD163 gene has been inactivated. Genetically modified swine having both alleles of the SIGLEC1 gene and/or both alleles CD 163 gene inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSV). Methods for producing such transgenic swine are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/