Burgin, Alex,Rao, Munagala,Singh, Jasbir,Kiselyov, Alexander,Gurney, Mark,Sandanayaka, Vincent
申请号:
AU2008326385
公开号:
AU2008326385B2
申请日:
2008.11.20
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention relates to substituted benzothiazoles, benzoxazoles - and theircounterparts having pyridine and pyrimidine rings replacing the benzene ring- that are are PDE4 inhibitors useful for treating stroke, myocardial infarct,and cardiovascular inflammatory conditions, to pharmaceutical compositionscomprising these compounds, and to methods for the treatment of stroke, myocardialinfarct, and cardiovascular inflammatory conditions in a mammal. The compoundshave general formula (I) in which A and B are carbocycles or heterocycles. A particularembodiment is formula (AB).